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Studio su operatori sanitari in sperimentazione clinica randomizzata:

“I risultati suggeriscono che la Vitamina D in personale altamente esposto previene l’infezione da SARS-CoV-2 senza eventi avversi e indipendentemente dallo stato di VACCINAZIONE.”

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Results

Of 321 recruited subjects, 94 VDG and 98 PG completed follow-up. SARS-CoV-2 infection rate was lower in VDG than in PG (6.4 vs. 24.5%, p <0.001). The risk of acquiring SARS-CoV-2 infection was lower in the VDG than in the PG (RR: 0.23; 95% CI: 0.09–0.55) and was associated with an increment in serum levels of 25-hydroxyvitamin D3 (RR: 0.87; 95% CI: 0.82–0.93), independently of VD deficiency. No significant adverse events were identified.

Conclusions

Our results suggest that VD-supplementation in highly exposed individuals prevents SARS-CoV-2 infection without serious AEs and regardless of VD status.